Search

Generic selectors
Exact matches only
Search in title
Search in content
Post Type Selectors
GET IN TOUCH
Brochure

Integrated cell line development solutions

Download PDF
Meeting challenges for the stable expression and purification of novel molecules.
Aragen's high throughput discovery service facilitates the evaluation of multiple therapeutic molecules. In combination with the development package, a lead therapeutic candidate with high quality and good manufacturability can be identified. This coupled with Aragen's Cell Line Development expertise using a royalty-free and regulatory-friendly platform makes Aragen your partner of choice.

Discovery services

  • Molecular design, protein engineering
  • Variant analysis through high through put transient expression
  • Developability services

Development services

  • Therapeutic and reagent cell lines
  • Extensive analytical capabilities including Biosimilar package
  • Upstream process development
  • Downstream process development
  • MCB preparation

The Aragen advantage

  • Experience that counts – Over 200 CLD programs performed
  • Expertise that delivers – Over 100 CLD programs Pre-IND/GMP
  • Stellar track record of success – Over 14 in Clinical development and 3+ commercial
  • Non-optimized titers up to 6g/L and RCB in 4 to 6-months

Cell line development expertise

Host cell lines

  • CHO DG44
  • CHO-GS
  • HEK293
  • SP2/0
  • NS0

Molecules

  • Antibodies
  • Bispecifics
  • Fusion proteins
  • Biosimilars
  • Cytokines
  • Hormones
  • Growth factors
  • Toxic proteins
  • Enzymes
  • Signaling protein

A robust and flexible CHO expression platform

 

Our platform is well-documented, regularly reviewed by global regulatory agencies and extremely competitive with respect to titers obtained and speed of delivery. We support μg to kg scales of requirement in a variety of life science and drug discovery applications. Our capabilities include therapeutic CLD, diagnostic reagents,high throughput screening, research tools and reagents, crystallography and cell based assay tools.