Recently there is a paradigm shift from batch manufacturing to continuous manufacturing. Hazardous reactions like Nitration, Azide Chemistry, Halogenations can be handled safely and efficiently. Cryogenic reactions: N-Butyl Lithium reaction/DIBAL reduction/Grignard reaction can be performed at sub-zero temperatures.
Other uses are Kinetically Fast, toxic and runaway reactions where better process control is required, High temperature Epimerization, and Alkylations and Flow photo reactions.