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Small Molecule Process R&D and Manufacturing

To consistently deliver value-added scientific solutions with speed and quality, while ensuring safety and compliance.

Chemistry and Technologies

  • Coupling Chemistry (Heck, Suzuki)
  • Fluorination/Bromination
  • Hazardous Chemistry
    • Azide
    • Cyanations
    • Nitrations
    • Lithium/Borane
    • DIBAL/Sodium Borohydride
    • POCl3
  • Peptides
  • Pressure reductions/reactions (up to 25 bar)
  • Chemo/Biocatalysis
  • Flow processing
  • Large Scale Chromatography

Operational Capabilities

  • Active across three sites for security of supply
  • 9 process blocks, 265+ KL capacity across three
    site 100L to 6000L, SS, GLMS, Hastelloy
  • Milling
  • cGMP and Non-GMP available
  • HPAPI facility – to 1 µg / m3 (OEB 4)
  • Operating pressure: full vac to 25 bar
  • Operating temperature: -80oc to 170oc
  • World class analytical support
  • Comprehensive set of analytical capabilities
    performed 100% in-house (nGMP& GMP)

Highlights

  • 3000+ scientists
  • 450+ global clients
  • Collaborations with 7 out of the 10 top pharma companies
  • 74 NCE projects
  • Sales diversity – North America (60%), Europe (30%), Asia Pacific (10%)
  • Over 15 independent customer audits in FY 2020-21

Formulation Development

  • Salt/Co-crystal/Polymorph studies
  • Solid orals, liquids, injectable, ophthalmic and semisolids
  • Integrated DS/DP development & supply
  • Supported by multiple state-of-the-art facilities
  • World-class scientific talent pool
  • Culture of safety and compliance always

Regulatory and EHS