Inflammation is an early event that is the underlying cause of most diseases, including cancer. The inflammatory condition is associated with an activated immune system, including activated immune cells and biomolecules. Inflammatory models of diseases are therefore critical to the understanding of disease etiology across colitis, psoriasis, multiple sclerosis, arthritis and fibrosis.
At Aragen, we employ animal models that show tissue-specific inflammation and utilize a variety of approaches, to evaluate novel treatments. Our preclinical research in immunology and inflammation focuses on arthritis and autoimmunity. Aragen scientists have expertise in preclinical investigations of the joints and lung functions in vivo, including bronchoalveolar lavage, cytology, immunohistochemistry, and analysis of biochemical, immunological and molecular parameters. Strong collaborations with various academic, governmental and industrial laboratories have enabled the development of several experimental models of immunology and inflammatory diseases.
